Dr. Gladden wearing glasses and a black Patagonia fleece smiling at the camera.
Founder & CEO of Gladden Longevity
Dr. Jeffrey Gladden, MD, FACC

Meet Dr. Jeffrey Gladden

Physician | Longevity Pioneer | Author | Speaker

Dr. Jeffrey R. Gladden, MD, FACC is a pioneering physician, longevity expert, and founder of Gladden Longevity, a cutting-edge health optimization and longevity clinic based in Dallas, Texas. A triple-board-certified cardiologist with more than four decades of clinical experience, Dr. Gladden has dedicated his career to transforming the way we understand aging, health, and human performance.

After decades practicing interventional cardiology and leading cardiovascular innovation, Dr. Gladden shifted his focus from treating disease at its end stages to addressing the root causes of aging and optimizing human vitality. Today, he is widely recognized as a leading voice in longevity medicine and the movement to help people Live Young for a Lifetime™.

Through his clinical work, research, writing, and speaking, Dr. Gladden empowers individuals to unlock their ageless potential by combining cutting-edge science, functional and regenerative medicine, and a holistic understanding of human health. His goal is for us at age 100 to have a 30 year old body and a 300 year old mind.

A Personal Quest for Longevity

Dr. Gladden’s work in longevity medicine began with a deeply personal turning point.

In his mid-50s, despite a successful medical career, he began experiencing weight gain, muscle loss, persistent fatigue, intermittent anxiety, and going over a cliff of depression. When conventional medicine offered little more than the explanation that he was “just getting older, why don’t you take an anti-depressant” he refused to accept that answer.

After doing a deep dive into the functional, integrative, and longevity medicine space he was able to understand why he had the issues he did and solve them. What took him two and half years can now be done in a matter of days. His turn around was so profound that he stopped asking how do I get better and started asking: “How good can I be and for how many years and decades can I carry this forward?

That question launched a personal investigation into setting up a practice that went beyond traditional and even functional medicine into the science of aging, vitality, and human performance optimization. Through research, experimentation, and clinical exploration, Dr. Gladden began integrating functional medicine, regenerative therapies, and advanced diagnostics from his own health journey into what has become Gladden Longevity.

The results were transformative.

His personal recovery and renewed vitality ultimately led to the creation of Gladden Longevity, where he now helps others pursue the same path toward optimized health, energy, and longevity.

Medical Career and Leadership

Dr. Gladden graduated with Honors in Medicine from Temple University School of Medicine, and was elected to the AOA medical honor society. Beginning a distinguished career in cardiovascular medicine.

Over the years, he has served in numerous leadership roles, including:

  • Founder of Advanced Heart Care a full service cardiology practice with ten offices and twelve doctors
  • He co-founded the Heart Hospital Baylor Scott and White with locations in Plano, Mckinney, Frisco, Denton and Dallas Texas
  • He served as Director of Strategic Development for the Hospital in its early stages
  • After transitioning to his current practice he stayed on as the Director of Heart Attack and Stroke Prevention and Cardiac Rehabilitation at The Heart Hospital Baylor Plano, for several years
  • Founder and Medical Director of Gladden Longevity
  • Served as CMO and Board Member at Scientia Cardio Access until it was acquired
  • Served as a Board Member at Scientia Vascular for over 15 years until it was acquired
Throughout his career, Dr. Gladden has combined deep clinical expertise with a relentless curiosity about the future of human health, and the human experience, pioneering approaches that blend preventive medicine, regenerative science, and advanced diagnostics with deep psychological and spiritual insights that resonate across multiple religious traditions.

Founder of Gladden Longevity

As the founder of Gladden Longevity, Dr. Gladden has developed a unique model of longevity medicine focused on optimizing four interconnected pillars of human vitality:

Life Energy
Longevity
Health
Performance
Environment

At the Gladden Longevity + Advanced Performance Center, individuals undergo comprehensive evaluations using advanced diagnostics, precision medicine, and personalized treatment strategies designed to enhance healthspan, vitality, and peak performance.

The clinic’s philosophy goes beyond traditional functional medicine, exploring the deeper drivers of aging such as cellular resilience, metabolic health, regenerative biology, and the complex interplay of biological systems.

Author and Thought Leader

Dr. Gladden is the author of the bestselling book:

100 is the New 30: How Playing the Symphony of Longevity Will Enable Us to Live Young for a Lifetime

In the book, he challenges conventional assumptions about aging and presents a new framework for longevity based on what he calls the “Symphony of Longevity™.” This model integrates mindset, resilience, regenerative medicine, and personalized health strategies to help individuals redefine their biological age and sustain vitality across their lifespan.

The book introduces several key ideas and questions, including:

  • What longevity means
  • How good can we be?
  • How do we “Live Young for a Lifetime”
  • How do we make 100 the New 30?
  • How do we live well beyond 120?
  • How do we develop a 300 year old mind
  • The concept of a “Mosaic of Biological Ages™”
  • The understanding that aging is exponential, not linear and that most longevity strategies are linear and not exponential
  • The role of life energy as psycho spiritual optimization to enhance the quality of life, by lowering stress, decreasing the rate of aging, improving resilience, and robustness, and enhancing recovery, regeneration and long-term vitality
  • Practical strategies to become an “Age Hacker™”
Through this work, Dr. Gladden invites readers to rethink aging and take ownership of their health trajectory.

Podcast Host and Educator

Dr. Gladden is also the host of The Gladden Longevity Podcast, where he interviews leading scientists, physicians, innovators, and thought leaders shaping the future of longevity medicine.

His conversations explore topics such as:

  • Age-hacking and longevity science
  • Regenerative medicine and human rejuvenation
  • The biology of life energy
  • Strategies to reverse biological aging
  • Mindset and purpose as drivers of health

Through the podcast and his speaking engagements, Dr. Gladden continues to inspire audiences worldwide to rethink what’s possible in human health and lifespan.

More About Dr. Gladden’s Podcast
Dr. Gladden wearing glasses and a black Patagonia fleece smiling at the camera.

Life Beyond Medicine

Dr. Gladden embodies the philosophy he teaches.

Today, he maintains a vibrant and active lifestyle, enjoying pursuits such as:

  • Surfing
  • Mountain biking
  • Hiking
  • Snowboarding
  • Running
  • Playing the guitar
He believes that longevity is not merely about extending lifespan, but about sustaining energy, curiosity, purpose, and meaningful connection throughout life.
Dr. Gladden wearing glasses and a black Patagonia fleece smiling at the camera.

Mission, Vision, Philosophy

Mission

To unlock the ageless potential within each individual through cutting-edge solutions that optimize healthspan, elevate performance, and extend longevity for both our valued clients and us.

Vision

Our vision is to redefine the human experience; to empower individuals to unlock their ageless potential, enabling them to thrive vibrantly at every stage of life.

Philosophy

Our philosophy is rooted in the belief that the conventional understanding of aging as a linear process is flawed. Instead, we recognize aging as an exponential challenge, and maintain that our capacity to ask meaningful questions, without attachment to our answers, provides innovative solutions to Live Young for a Lifetime.

Achievements and Impact

Speaking & Media Topics

Dr. Gladden regularly speaks on topics including:

  • The Hero’s Journey: How to Live Young for a Lifetime
  • Age Hacking: Making 100 the New 30
  • The Science of Regenerative Longevity
  • Reversing Biological Age
  • The Future of Longevity Medicine
  • Energy and Vitality Beyond Midlife

Contact Information

For speaking engagements, media inquiries, interview requests, or partnership opportunities, please contact:

Gladden Longevity

200 O’Connor Ridge Blvd, Suite 100

Irving, TX 75038

Live Young for a Lifetime

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